Evolvability and Single-Genotype Fluctuation in Phenotypic Properties: A Simple Heteropolymer Model
نویسندگان
چکیده
منابع مشابه
Evolvability and single-genotype fluctuation in phenotypic properties: a simple heteropolymer model.
Experiment showed that the response of a genotype to mutation, i.e., the magnitude of mutational change in a phenotypic property, can be correlated with the extent of phenotypic fluctuation among genetic clones. To address a possible statistical mechanical basis for such phenomena at the protein level, we consider a simple hydrophobic-polar lattice protein-chain model with an exhaustive mapping...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2010
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2010.02.046